|
Virtually every major medical advance of the last century has relied on animal research. The knowledge gained through such
research has led to the ability to treat, prevent or eradicate diseases that
once killed millions of people every year. Animal research has also resulted in
many lifesaving treatments and therapies for pets and farm animals as well.
When studying human diseases, nonhuman primates
provide one of the best animal models. Humans and monkeys bear a close genetic
relationship, reflected in many anatomical, behavioral, developmental,
physiological, and reproductive similarities. Because of these close
similarities, nonhuman primates have played a critical role in biomedical and
behavioral research.
For example, monkeys are susceptible to an
immunodeficiency virus similar to HIV, making them ideal for the study of AIDS
and potential vaccines and treatments.
Similarities in the central motor pathways between
monkeys and humans have led to the development of safe and effective
interventions to slow the progress of Parkinson's disease.
Monkeys in breeding colonies can live well past their
normal lifespan in the wild, providing opportunities for research on aging-related diseases, such
as Alzheimer's disease and changes associated with the menopause
and reproductive senescence. Studies at the CNPRC have led to successful clinical
trials and beneficial treatment of people with mild forms of Alzheimer’s
Disease.
Monkeys are the only mammalian animal model with
menstrual cycles and hormonal patterns comparable to humans. Thus, reproductive
research provides crucial insights into fertility, pregnancy and menopause.
These are just a few of the
many examples of how research in nonhuman primates has extended our fundamental
knowledge of how the human body functions in health and disease.
|