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The Brain, Mind, and Behavior Unit provides
services, training, consulting and collaborative expertise in the areas of
basic neuroscience, stress physiology, psychoneuroimmunology, cognitive
neuroscience, and psychosocial processes in nonhuman primates. Particular
emphasis in the Unit is on studying the interrelations of processes at multiple
levels of analysis: social, psychological, neuroendocrine, and neurobiological.
Researchers in the Brain, Mind and Behavior Unit
direct their efforts to a diversity of programs:
- Understanding the physiological and health consequences of chronic stress
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The interconnections of various limbic system structures (the hypothalamus,
pituitary, amygdala and, hippocampus) which function to regulate our emotions
and memory, as well as playing a role in social and nonsocial behavior
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Furthering our understanding of primate biobehavioral organization and
psychoneuroimmunology: understanding individual difference factors such as
personality and temperament in primates, and how such factors contribute to
health and immunodeficiency disease progression, and to behavioral,
physiological, and social organization
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Primate biosocial behavior and social processes: the factors contributing to
the development and maintenance of affiliative social relationships in adult
and immature individuals of both sexes. A related topic of equal concern is the
functional significance of affiliative relationships as reflected in their consequences
for an individual's competence, health, and well-being.
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The neuroendocrine mechanisms contributing to the generation and maintenance of
primate social systems: psychosomatics and the sociophysiology of stress and
reproduction in various species
- Studies in aged nonhuman primates: spontaneous impairments in learning and memory; temporal
development of these cognitive impairments and their association with other
biomarkers of aging, such as reproductive senescence; use of neurotrophic
factors in neurodegenerative diseases (neurotrophic factors influence a wide
variety of growth, development, and function in brain cells, and play important
roles in behaviors such as feeding, depression and learning).
- Successful gene therapy research with geriatric monkeys is now being used to treat human patients with mild Alzheimer's disease. Continuing studies are aimed towards effective
treatments for more severe forms of Alzheimer’s Disease as well as Parkinson’s
Disease and other neurodegenerative disorders.
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